A 19 Month’s Old African Female with Gluteal Yolk Sac Tumour: A Case Report and A Review of Literature
Uchendu Obiora Jude &Odion-Obomhense Helen
1Department of Histopathology, Delta State University Teaching Hospital, Oghara, Delta State
2Department of Pediatric Surgery, Delta State University Teaching Hospital, Oghara, Delta State
Email: ojlinksent@yahoo.com
ABSTRACT
Primary Yolk sac tumour (YST) of extragonadal site is a very rare tumour, usually arising from malignant transformation of misdirected primordial germ cell on transit from the yolk sac to gonads. The present study reports a primary YST of the gluteus in a 19 years old African child presenting with acute urinary retention and constipation. Complete tumour excision was done resulting in relief of urinary and bowel symptoms. In the face of limited investigation tools, light microscope observation of Schiller-Duvall bodies in histopathology specimens, as seen in this case, is diagnostic. Complete excision with Platinium-based chemotherapy has been shown to gives excellent 5 year survival. Alpha fetoprotein (AFP) is useful marker in monitoring response to therapy. Poverty and unavailability of advanced diagnostic tools are however major challenge in diagnosis of atypical cases in Africa.
Key word: Yolk sac tumour, Gluteal mass, Histology
