Histomorphology of Intracranial Tumors in Benin-City, Nigeria
1Udoh MO, 2Udoh DO, 1Aligbe JU, 1Olu-Eddo AN, 1Ekanem VJ, 1Akhiwu WO, 1Obaseki DE, 1Ugiagbe EE, 1Forae GD, 1Obahiagbon I, 1Imasogie DE.
1Department of Histopathology, University of Benin Teaching Hospital, Benin City
2Neurological Surgery Unit, Department of Surgery; University of Benin Teaching Hospital, Benin City
E-mail: moludoh@yahoo.co.uk, Corresponding Author: Dr. Mojisola Olutayo Udoh
ABSTRACT:
Intracranial tumors are a heterogenous group of lesions attracting significant morbidity and mortality. Before the establishment of neurosurgical services in the University of Benin Teaching Hospital
in 2006, patients with intracranial surgical pathologies in the Edo-Delta axis (and several surrounding states) of Nigeria travelled far to other regions of the country and abroad for diagnoses and treatment.
However, in the past thirteen years, a cohort emerged, of patients with intracranial tumors who were diagnosed and treated in our tertiary health institution. To describe the histomorphology of intracranial tumors in the Edo-Delta region of Nigeria. A retrospective database study of intracranial tumors diagnosed at the histopathology department of our hospital between July 2006 and December 2018. Demographic and clinical data were retrieved from the records of the department. Data was analyzed using
SPSS 20.0. A total of 150 (65 males and 85 females) intracranial tumors were diagnosed during the period studied i.e. male-female ratio of 1:1.3. Peak incidence was in the 4th decade and mean age was 39.76±20.30.
Meningiomas were the commonest intracranial tumors (47.3%); followed by gliomas (23.3%), metastasis (6%) embryonal tumors and pituitary adenomas contributed 5.3% each, locally invasive head and neck
tumors (4%). Astrocytomas constituted 68.6% of gliomas; glioblastomas alone constituted 45.83% of astrocytic lesions, 31.4% of all gliomas and 7.3% of intracranial tumors. The commonest intracranial tumors in children were gliomas (45.8%), mostly ependymomas and pilocytic astrocytomas. Histopathological diagnosis remains pivotal in the management of intracranial tumors, predicting behavior, and determining treatment and the prognosis of the lesion. The patterns of occurrence of intracranial tumors in this study, are similar to that described elsewhere
Keywords: Intracranial Tumors; Central nervous System, Brain tumors, Histopathology
