• 0

Anti-Trypanosomal Efficacy of Garcinia kola Aqueous Seed Extract as an Alternative Remedy in Treatment of Trypanosomiaisis Disease

Moses Oluwaseun Abiodun, Anthony Obinna Ekesiobi & Leonard Chikwado Onyenweife

ABSTRACT

This study investigated trypanosomal activity, haematological and lipid profile effects of Garcinia kola aqueous seed extract and compared with Berenil (Diaminizene aceturate) drug in treatment of typanosomiasis induced Wistar rat.  The extract was obtained through Maceration method with distilled water, In vitro activity of the extract and Berenil drug was determined using rapid matching techniques at 3 hours post incubation period with different doses of the extract and 3.5mg of Berenil drug. In vivo study was done using 62 Wister rats, divided into 10 groups. Group A (normal control): non infected and non -treated, Group (B-H) were infected by intra peritoneal inoculation of 1mL of parasitized blood containing 1.0´105/ml of T. brucei gambianse parasites and treated with different doses of Garcinia kola seed extract, 200 – 1400mg, Group I: infected and treated with standard drug dose, Group J: infected and non- treated (Pathological control). The treatment lasted for 21 days at 3 days interval.  Hematological and lipid profile effects were determined by colorimetric method. Data were analyzed statistically using Anova at 0.01 significant differences. Various hematological and lipid profile effects were observed in all the extract treated and control groups. Garcinia kola seed extract exhibited trypanosostatic at dose of <400mg and trypanocidal activity at doses > 400mg in both in vitro and in vivo, compared with trypanocidal activity of standard Berenil drug dose. Garcinia kola seed extract produced moderate side effect on haematological and lipids profile parameters of wistar rat at doses <400mg in the extract treated groups when compared with Berenil drug which produced higher toxicity effect on heamatological and lipid profile parameters at standard dose. This study revealed that Garcinia kola aqueous seed extract may be used to design drug for the treatment of trypanosomiasis at lower concentration therefore, the use of Berenil drug in human and animal treatment should be discontinued.

Keywords: Trypanosomiasis, Trypanosostatic, Wister rat,Berenil, Garcinia kola.  




  • 0

Social Media Usage and the Development of Eating Disorders among Secondary School Adolescents in Ikeja, Lagos

Ajuzie Nnenna Choice1, Ogun Ireti B1, Ogbonnaya Faith Chidiebube2, Ukangwa Ngozi Angela2, Omotoye Ayodeji A1, Awoyinka Rachael I3, Emmanuel Godspresence C.

ABSTRACT

Eating disorders has been argued and characterized to been more prevalent in “developed” countries because of their beauty standard emphasis on thinness, it has been proposed that these “developed” countries with a higher prevalence of eating disorders shape developing countries into the development of eating disorders. The main objective of this research is to assess social media usage and the development of eating disorders among secondary school adolescents in Ikeja, Lagos using a cross- sectional study design and 232 respondents were selected for the study. Majority of the respondents (69.0%) were female and 31.0% were male of respondents. Less than average of the respondents (34.1%) were 15 years of age, while 4.7% were 18 years of age. More than average of the respondents (51.7%) Public Secondary School while the least percentage (48.3%) were in Private Secondary School. Majority of the respondents had normal Body Mass Index (70.3%), 20.3% were overweight, 9.5% obese and 0.4% underweight. Almost all the respondents (93.5%) use social media platforms above 30mins and 6.5% used social media platforms below 30mins while more than quarter of the respondents use Whatsapp (46.6%), Tiktok (27.2%) and Snapchat (28.9%) 5 or more times a day. 54 respondents (23.3%) scored positive (scored ≥ 20) on the EAT-26 thus representing the prevalence rate of eating disorder. There is significant relationship between social media usage and awareness of the calorie content of the food (p=0.01).

Key words= Eating Disorders, Adolescents, social media


  • 0

Effects of Moroccan Watermelon Mosaic Virus (MWMV) on Growth, Some Elemental and Phytochemical Composition of the Leaf of Cucumeropsis edulis Naudin

Akpainyang, N. U.

ABSTRACT

Effects of Moroccan watermelon mosaic virus (MWMV) on Growth, Some Elemental and Phytochemical Composition of the Leaf of Cucumeropsis edulis Naudin were carried out. Test plants arranged in complete randomized designed were mechanically inoculated at 8 days except the control. Two months post inoculation, infected and healthy plants were harvested and studied for growth parameters using graphical method, weighing and linear measurements. The elemental contents of both infected and uninfected plants were evaluated using standard methods proposed by Association of Official Analytical Chemists. Phytochemical tests were performed on the plant extracts following standard procedures. The results showed that MWMV caused significant reductions (P<0.05) in all the growth parameters of Cucumeropsis edulis with mean shoot height and dry leaf weight being 52.82 ± 6.15 cm and 0.40 ± 0.31 g in infected sample compared to the corresponding healthy values of 75.00 ± 13.24 cm and 1.23 ± 1.00 g obtained for the control. All the elemental contents of MWMV – infected plant were significantly (P<0.05) reduced with zinc having the least mean value of 0.08 ± 0.21 mg/100 g while uninfected sample had 1.83 ± 0.00 mg/100 g. The phytochemical results of the crude extracts of C. edulis revealed the presence of alkaloid, flavonoid, saponin, tannin and terpene, all in varying concentrations in both the infected and healthy plant samples. There is need to control the spread of this virus through phytosanitational measure, use of resistant variety and effective quarantine services. This will provide food security and poverty alleviation.

Keywords:     Cucumeropsis edulis, Virus, Growth, Elemental and Phytochemical Composition.


  • 0

Evaluation of Socio-Economic Factors Determining Academic Achievement of Women Learners in Literacy Education in Niger State, Nigeria

Ezesuokwu, Johnpaul Ejike, Dr. A. A. Adelakun, Dr. M. F. Olajide and Dr. D.A. Danasabe

ABSTRACT

This study investigates the impact of socio-economic factors, particularly family background, on the academic achievement of women learners enrolled in literacy education programs in Niger State, Nigeria. Using a descriptive survey research design, data were collected from a sample of 390 women enrolled in adult literacy and skill acquisition centers. The findings reveal that family background, including factors such as support, cultural beliefs, material resources, and family dynamics, significantly influences women’s literacy achievement. Supportive families were found to encourage regular attendance, provide essential resources, and create conducive study environments, leading to better academic performance. However, financial constraints and cultural limitations still pose challenges for some learners. The study concludes that family involvement is crucial for the academic success of women in literacy education. To enhance the effectiveness of these programs, recommendations include providing financial aid, improving access to educational resources, raising community awareness, offering flexible learning schedules, and encouraging family support. Addressing these barriers could improve literacy outcomes and socio-economic opportunities for women in Niger State.

Keyword: Socio-economic factors, academic achievement, women learners


  • 0

Syrian Conflict and Its Implication on Peace and Security in African Countries

Ibiam Sunday Mba

INTRODUCTION

In this era, we continue to witness evolving scenarios not even good for deviants to experience. Decades ago, kidnapping, terrorism and other forms of insurgency were heard far of in Gaza strip, Palestine (Middle East). People imagine how the culprits and victims will look like; the same feeling was also common at hearing about coup d’état and later catching sight at a suicide bomber whether male or female. The expression on faces, ask, if it is real? However, the contagious effects of successful young coup plotters inspired by some revolutionary literatures around the world evidently were rampant in Africa during military regimes. Politics, religion, trade etc are universal doctrine for that it’s operational manifestations positively and negatively is copied fast in one-world universality orchestrated by globalization. The advancement recorded in westernization, liberalization, modernization etc ensures that any form of disposition is in fact highly copied and practiced around the world following a coincidental need or by way of fair abuse or by practical adoption as ethics. Indeed, the quick spread of what is adjudged good and bad have also responded to the increasing wave of the 21st century.


  • 0

An Account of Muslim Intellectual Feats and Contributions in the Fields of Sciences

Nasir Muhammad Abdulhameed

ABSTRACT

The acquisition of knowledge encouraged by Islam is not only meant for mundane benefits but the discovery of truth about the doctrine of belief in God. The primary sources of Islam motivated the classical Muslims to acquire and master various branches sciences. Thus, the spread of Islam beyond Arabia brought the Muslims into direct contacts with the cultures and traditions of Persians, Greek, Byzantine, Syrians, Egyptians and Indians. These contacts resulted in the acquisition of new ideas, knowledge, and more awareness about the practices of those communities. Muslims acquired the scientific ideas of those communities and synthesized them with what they had in the tradition of Islam. They refined the scientific ideas and developed new principles in various fields of sciences. This paper applies theoretical method in presenting a brief account of the contributions of Muslims scientists in the fields of astrology, astronomy, medicine, mathematics physics and chemistry. The aim is find out how the Muslims in the classical period learned the works of past scientists, clarified them and developed new scientific principles. However, Muslims did not only acquire knowledge from the Persians, Greek, Byzantine, Syrians, Egyptians and Indians, they combined such knowledge with what obtained in the tradition of Islam. They improved the existing scientific principles, developed new ones, and wrote original works. Such works became leading materials in sciences in the institutions of learning throughout the world. The translation of the work into Latin helped modern Europe to become acquainted with scientific principles developed by early scientists. Thus, the advancement recorded in modern sciences owes a lot to the efforts of Muslims in the preservation past works, systematizing of scientific principles and invention of new methods of tests and experiments. 


  • 0

An Exploration of Ethical Behaviour among Accountancy Trainees in Nigeria

Kabir Ibrahims

ABSTRACT

This paper examines the ethical behaviour among 32 accountancy trainees undergoing professional training in Nigeria. Qualitative approach, using semi structured interview, as well as thematic analysis was carried out during an interview session with graduate accountants to examine their perspectives on ethical standards and development. The study found that aspirant professional accountants encountered challenges that were directly related to the knowledge and training they had received as undergraduate students. Furthermore, the study found that unethical behaviour practice is not connected to understanding professional ethics. Thus, in order to mitigate this unwelcoming scenario, this study recommends that, acquiring practical skills through informal learning is essential for mitigating unethical professional behaviour among accounting practitioners in Nigeria.

Keywords: accountancy trainees, ethical behaviour, professional development


  • 0

A Comparative Study on The Mechanical Properties of High Strength Concrete Made with Basalt and Granite as Coarse Aggregate

1Dapia, Z.A., 2Zakka, P.W., 2Agboju, S.E, 2Cyril, C.K., and 2Dusu, A.A

ABSTRACT

High strength concrete (HSC) of grade M60 was prepared and cast in cubes of 100 mm x 100 mm x 100 mm and beams of 100 mm x 100 mm x 500 mm to compare the mechanical properties of the concrete with regards to basalt and granite as coarse aggregate. The aim of this research is to compare the mechanical properties of high-strength concrete made with basalt and granite as coarse aggregates as well as the effects of mild temperature on the strength of the concrete. Compressive strength tests, flexural strength tests, density tests were conducted as well as effects of heat-treatment of 2000C for 24, 48 and 72 hours on the cubes to observe its effect on the concrete. With regard to the compressive strength tests, cubes made with granite posed to have a higher compressive strength (52 N/mm2 at 28 days of curing) as compared with cubes made with basalt (achieving a strength of 50 N/mm2 at 28 days of curing). For the flexural strength tests, the beams made with basalt developed a strength of at 28 days while beams of basalt developed which is lesser compared with the strength of beam made with granite. The heat-treatment of the concrete resulted in developing the compressive strength of the concrete to 53.5 N/mm2 for granite while for basalt resulted in 52 N/mm2. From the results obtained from this study, it can be deduced further that, HSC made with basalt has poor thermal conductivity as compared with HSC made with granite and hence, could be used for constructing areas which might be exposed to high temperature. Also, with regards to areas of high magnitude of loading, impact or wear such as, pavements, HSC made with granite would be most appropriate as compared to HSC made with basalt.

Keywords: High Strength Concrete, Mechanical Properties, Basalt, Granite and Coarse aggregates.


  • 0

Strength Characteristics of Self-Compacting Concrete Containing Quarry Stone Dust and Glass Cullet

Alikori Oghenekeno Favour, Gana A.J., and Charles Prince Ikata

ABSTRACT

Self-compacting concrete (SCC) is a highly flow-able type of concrete that spreads into the form without the need for mechanical vibration. This study explores the feasibility of using quarry stone dust and glass cullet as partial replacement for fine aggregate in the production of SCC. This project was done to assess how SCC will behave with quarry stone dust and incremental percentage of glass cullet in 0%, 10%, 20% and 50%. Making use of the mix design the samples were cast and the necessary test such as sieve analysis, flexural strength test, compressive strength test, bulk density water absorption and slump test were carried out on three samples per mix to get the average results. The result obtained showed that the mix of quarry stone dust and 20% of glass cullet has the highest compressive strength at 17.01 ,21.09 , 23.23  for 7, 14 and 28 days curing period respectively than other mix, the sample with the highest flexural strength was also the 20% glass cullet mix sample at 3.73 ,4.53  and 4.8  for 7,14 and 28 days curing period. The water absorption rate of samples when compared had a decrease with the amount for glass cullet percentage available in the mix of with the lower was at 50% of glass cullet at 4.11% and 4.39% at 2 and 24 hours respectively at 28 days. This research validates the use of quarry stone dust and glass cullet to improve workability, compressive strength, flexural strength and also water absorption rate which is necessary to predict the long-term performance of the concrete.

Keywords: Strength, Characteristics, self-compacting, concrete, quarry stone dust, cullet


  • 0

Entrepreneurship And Sports: A Catalyst for Economic Development

Mohammed Idris Jika, Kabiru Abubakar and Salihu Isah Lemu

ABSTRACT

This paper explores the dynamic interplay between entrepreneurship and sports as catalysts for national development. The review highlighted how entrepreneurial endeavors within the sports industry contribute significantly to economic growth, social cohesion, and cultural enrichment. The paper through literatures unveiled the multifaceted impacts of sports entrepreneurship on national progress. The paper also examines how sports provide a fertile ground for entrepreneurial opportunities, ranging from sports technology and equipment innovation to event management and sports tourism. The paper also acknowledges the challenges and considerations in harnessing the full potential of sports entrepreneurship for national development. It discusses issues such as access to resources, infrastructural development, and equitable distribution of benefits, emphasizing the need for strategic policies and collaborations between governments, private sector entities, and sporting organizations. In conclusion, this review paper highlights the undeniable synergy between entrepreneurship and sports in driving national development. It recommends the need for continued research, policy innovation, and collaborative efforts to maximize the transformative impact of sports entrepreneurship on economies and societies around the world.

Keywords: Entrepreneurship, Sports, Opportunities, Challenges and Innovation