Effect of Ethanol Extract of Momordica Balsamina and Some Antioxidants on Biomarkers in Broilers with a Virulent Newcastle Disease Virus

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Effect of Ethanol Extract of Momordica Balsamina and Some Antioxidants on Biomarkers in Broilers with a Virulent Newcastle Disease Virus

Agang, I. D.1 ; Sai:du, L.2; Audu, P.A.3; Suleiman, M.M.4; Gambari, K.O.5;  Hambagda, F.O.6;  Riki, F.7; Darlinton, K.O.8; Akushielem, G.C.9; Diugwu J.10; Ayomoh, E.11; Okonkwo  K.O12 & Holms, M.J.13

ABSTRACT

Newcastle disease poses a serious threat to the poultry industry as it has economic and ecological impact on pet, free living as well as domestic birds. The aim of the study was to evaluate the effects of some antioxidants and Momordica balsamina on haematological parameters in broilers challenged with ND Kudu 113 Virus. Two-hundred-day-old broilers were procured from a hatchery in Ibadan. The chicks were brooded for 4 weeks then divided into 8 groups (1 ml/L) of 20 chicks each. Each group was housed in a pen on deep litter system with a floor space of 1.14 cm2 /bird with the exception of G1 which was housed outside the faculty. All the experimental groups except G1 were challenged with NDV Kudu 113 strain but G1 was given 2 ml of distilled water at 5 weeks of age. Birds in G2 were challenged with NDV and not treated with any antioxidant but given 2 ml of water at 5 weeks of age. Birds in G3 were administered vitamin C600 mg tablets in 2L of water at the rate of 2 ml of water per bird orally. Birds in G4 were treated with vit. E 400 mg/ml and challenged. Birds in G5 were treated with selenium-vit Eat I ml/L in 2 L of water /bird orally. Birds in G6 were treated with ethanol extract of M. balsamina leaves 400 mg/ml in 2 L of water orally. Birds in G7 were administered ethanol extract of M. balsamina roots 200 mg/ml in 2 L of water orally. Birds in G7 were administered ethanol extract of M. balsamina roots 200 mg/ml