AMELIORATIVE EFFECTS OF GREEN TEA ON POTASSIUM BROMATE INDUCED PANCREATIC DAMAGE OF ADULT WISTAR RATS
Okafor I.J & Elemuo C.O
Department of Anatomy
Faculty of Basic Medical Sciences
Chukwuemeka Odumegwu Ojukwu University Uli, Anambra State, Nigeria
Email: stanleyelemuo@yahoo.com
ABSTRACT
Bromate is a byproduct of ozonation process that is sometimes used for the disinfection of municipal drinking water. Potassium bromated is metabolized into harmful substances within different organs, and generally target those specific places once produced. This led to the study of its effects on the pancreas following oral administration of honey. Twenty wistar rat weighing averagely 150g were divided into four groups (n=5). Group A served as the control group while groups (B, C, D) were the experimental groups which received potassium bromate only, group C received green tea extract only while group D received green tea extract and potassium bromate all using orogastric tube, usually between the hour of 9am to 10am at concentration of 1.0ml for green tea extract and 0.7ml for potassium bromate. The result of the study showed acute inflammation of the islet of Langerhans with few regeneration pancreatic tissue in the honey treated group.
Keywords: potassium bromate, pancreas, honey.
